Isothermal titration calorimetry of ion-coupled membrane transporters
نویسندگان
چکیده
منابع مشابه
Isothermal titration calorimetry of ion-coupled membrane transporters
Binding of ligands, ranging from proteins to ions, to membrane proteins is associated with absorption or release of heat that can be detected by isothermal titration calorimetry (ITC). Such measurements not only provide binding affinities but also afford direct access to thermodynamic parameters of binding--enthalpy, entropy and heat capacity. These parameters can be interpreted in a structural...
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ژورنال
عنوان ژورنال: Methods
سال: 2015
ISSN: 1046-2023
DOI: 10.1016/j.ymeth.2015.01.012